Nicotine Sulfate 40%

Hazards Identification

SPECIAL INDICATION OF

HAZARDS TO HUMANS AND THE ENVIRONMENT

Toxic in contact with skin

and if swallowed. Very toxic by inhalation. Irritating to eyes,

respiratory system and skin. Possible risk of harm to the unborn child.

Composition/Information on Ingredients

Product Name	:	(-)-NICOTINE HEMISULFATE 40% AQUEOUS SOLUTION
CAS	:	65-30-5
Formula	:	(C20H28N4) H2O4S
Molecular Weight	:	422.6AMU
Synonyms	:	ENT 2,435* 1-1-Methyl-2-(3-pyridyl)-pyrrolidine sulfate * (S)-3-(1-Methyl-2-pyrrolidinyl) pyridine sulfate(2:1)*  1-3-(1-Methyl-2-pyrrolidyl) pyridine sulfate* Nicotine sulfate* Nikotinsulfat(German)* Pyridine,3-(1-methyl-2-pyrrolidinyl)-,(S)-,sulfate(2:1)* Pyrrolidine,1-methyl-2-(3- pyridyl)-, sulfate* Sulfate de nicotine (French)

First Aid Measures

AFTER INHALATION

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

AFTER SKIN CONTACT

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

AFTER EYE CONTACT

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

AFTER INGESTION

If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately

Fire Fighting Measures

EXTINGUISHING MEDIA

Suitable: Water spray,carbon dioxide, dry chemical powder, or appropriate foams. SPECIAL RISKS

Specific hazard(s): Emits toxic fumes under fire conditions. SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS

Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL EVACUATE AREA.

PROCEDURE(S) OF PERSONAL PRECAUTION(S)

Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.

METHODS FOR CLEANING UP

Cover with dry-lime, sand, or soda ash. Place in covered containers using non-sparking tools and transport outdoors. Ventilate area and wash spill site after material pickup is complete.

Handling and Storage

HANDLING

Directions for Safe Handling: Do not get in eyes, on skin, on clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.

STORAGE

Conditions of Storage: Keep tightly closed.

Exposure Controls/Personal Protection

ENGINEERING CONTROLS

Safety shower and eye bath. Use only in a chemical fume hood.

GENERAL HYGIENE MEASURES

Wash contaminated clothing before reuse. Wash thoroughly after handling.

PERSONAL PROTECTIVE EQUIPMENT

Respiratory Protection: Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) with respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.

Hand Protection: Compatible chemical-resistant gloves.

Eye Protection: Chemical safety goggles.

Physical and Chemical Properties

Appearance Color: Brownish Liquid
Property	Value		Property	Value
pH	N/A		Viscosity	N/A
BP/BP Range	N/A		Vapor Density	N/A
MP/MP Range	N/A		Saturated Vapor Conc.	N/A
Flash Point	N/A		Evaporation Rate	N/A
Flammability	N/A		Bulk Density	N/A
Autoignition Temp	N/A		Decomposition Temp.	N/A
Oxidizing Properties	N/A		Solvent Content	N/A
Explosive Properties	N/A		Water Content	N/A
Explosion Limits	N/A		Surface Tension	N/A
Vapor Pressure	N/A		Conductivity	N/A
SG/Density	N/A		Miscellaneous Data	N/A
Partition Coefficient	N/A		Solubility	N/A

Stability and Reactivity

STABILITY

Stable: Stable

Materials to Avoid: Strong oxidizing agents.

HAZARDOUS DECOMPOSITION PRODUCTS

Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.

HAZARDOUS POLYMERIZATION

Hazardous Polymerization: Will not occur

Toxicological Information

RTECS NUMBER: QS9625000 ACUTE TOXICIT LD50 Oral Rat 50 mg/kg LC50 Inhalation Rat 22 mg/m3 LD50 Skin Rat 285mg/kg Remarks : Behavioral:Excitement. Behavioral:Convulsions or effects on seizure threshold. Behavioral:Tremor. LD50 Oral Mouse 8.55 mg/kg Remarks: Lungs, Thorax, or Respiration:Dyspnea. Behavioral:Tremor. Behavioral:Muscle contraction or spasticity. LD50 Intraperitoneal Mouse 10200 UG/KG LD50 Intraperitoneal Cat 20 MG/KG LD50 Skin Rabbit 50 mg/kg LD50 Oral Pigeon 75 mg/kg LD5O Oral Quail 316 mg/kg LD50 Oral Duck 75 mg/kg LD50 Oral Bird {wild} 32 mg/kg SIGNS AND SYMPTOMS OF EXPOSURE Extreme nausea, vomiting, evacuation of bowel and bladder, mental confusion, twitching, convulsions. Exposure can cause: ROUTE OF EXPOSURE Skin Contact: May cause skin irritation. Skin Absorption: Toxic if absorbed through skin. Readily absorbed through skin. Eye Contact: May cause eye irritation. Inhalation: Material may be irritating to mucous membranes and upper respiratory tract. Ingestion: Toxic if swallowed. TARGET ORGAN INFORMATION Skeletal muscle. nerves. CHRONIC EXPOSURE – TERATOGEN Species: Mouse Dose: 1670 MG/KG Route of Application: Intraperitoneal Exposure Time: (6-15D PREG) Result: Specific Developmental Abnormalities: Craniofacial (including nose and tongue). Effects on Embryo or Fetus: Other effects to embryo. Effects on Embryo or Fetus: Fetotoxicity (except death, e.g., stunted fetus). CHRONIC EXPOSURE – REPRODUCTIVE HAZARD Result: May cause reproductive disorders.

Ecological Information

No data available

Disposal Considerations

SUBSTANCE DISPOSAL

Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local environmental regulations.

Transport Information

RID/ADR UN#: 1658 Class: 6.1 PG: II Proper Shipping Name: Nicotine Sulfate, solution IMDG UN#: 1658 Class: 6.1 PG: II ProperShipping Name: Nicotine Sulfate, solution Marine Pollutant: No Severe Marine Pollutant: No lATA UN#: 1658 Class: 6.1 PG: II Proper Shipping Name: Nicotine Solution, suolution Inhalation Packing Group I: No

Regulatory Information

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES

INDICATION OF DANGER: T+ Very toxic.

R-PHRASES: 24/25/-26-36/37/38-63

Toxic in contact with skin and if swallowed. Very toxic by inhalation. Irritating to eyes, respiratory system and skin. Possible risk of harm to the unborn child.

S-PHRASES: 26-36/37/39-45-28 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves, and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). After contact with skin, wash immediately with plenty of soap and water.

Other Informatipon

WARRANTY

The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. BGP™ International shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.

DISCLAIMER

For Industrial use only. Not for drug, household or other uses.

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