Nicotine polacrilex is a nicotine compound mainly used as a nicotine source. Nicotine is compounded with polacrilex resin to form Nicotine polacrilex to provide desired drug release properties
Nicotine polacrilex , chemically is a weak carboxylic cation exchange resin prepared from methacrylic acid and divinyl benzene, in complex with nicotine.
C10H14N2 x (C10H10C4H6O2)y
Nicotine polacrilex USP contains not less than 95 % and more than 115 % of labeled amount of nicotine on anhydrous basis.
Nicotine polacrilex is used in the manufacture of smoking cessation products classified as smoking deterrents like nicotine polacrilex chewing gums.
Nicotine Polacrilex gums are nicotine-containing compounds that slowly release nicotine into the mouth when chewed and placed between the cheek and gum. Smoking used as source of nicotine is associated with many other harmful chemicals and tar also going into the body.
Following chewing, nicotine is released from an ion exchange resin in the gum product, providing blood nicotine levels approximating those produced by smoking cigarettes. The amount of nicotine released depends on the rate and duration of chewing.
Mainly used for smokers wishing to give up the smoking habit. This is considered as an initial aid, with the ultimate goal being abstention from all forms of nicotine.
Other nicotine based smoking cessations products are :
Nicotine trasdermal systems - patches
Nicotine nasal spray
Nicotine oral inhalers
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