BGP™ group WebData

	NICOTINE SULPHATE 40%
	NICOTINE ALKALOID 95%
	NICOTINE USP/EP
	NICOTINE BITARTRATE DIHYDRATE
	NICOTINE POLACRILEX USP/EP15%
	NICOTINE POLACRILEX USP/EP 20%
	COTININE
	CUPROUS CHLORIDE
	POTASSIUM NITRITE

Product Name

NICOTINEBITARTRATE DIHYDRATE

Product Number

A06

Company

BGP International
Post-Malosan
Dist-Mehsana
State-Gujarat
India-382816

Technical Phone

91-9825073320

Fax

91-2646-227375

E-mail Address

hkt@narmada.net.in

PECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENTS

Very toxic by inhalation, in contact with skin and if swallowed.Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environmen.

Product Name	:	NICOTINE BITARTRATE
CAS	:	65-31-6
Formula	:	C10H14N2.2C4H606
Molecular Weight	:	462.2AMU

AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. call a physician.

AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

AFTER INGESTION
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.

EXTINGUISHING MEDIA
Suitable: Water supply, Carbon dioxide, Dry chemical powder .

SPECIAL RISKS
Specific hazard(s): Emits toxic fumes under fire conditions.

SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL EVACUATE AREA.

PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.

METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in eyes, on skin, on clothing. Avoid prolonged or repeated exposure.

STORAGE
Conditions of Storage: Keep tightly closed.

ANDLING
Directions for Safe Handling: Do not get in eyes, on skin, on clothing. Avoid prolonged or repeated exposure. Do not breathe vapor.
STORAGE
Conditions of Storage: Keep tightly closed.

ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.

GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after handling.

PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type NI00 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sale means of protection, use a full-face supplied air respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.

Appearance

Physical state: Solid

Property

Value

Property

Value

N/A

Viscosity

N/A

BP/BP Range

N/A

Vapor Density

N/A

MP/MP Range

N/A

Saturated Vapor Conc.

N/A

Flash Point

N/A

Evaporation Rate

N/A

Flammability

N/A

Bulk Density

N/A

Autoignition Temp

N/A

Decomposition Temp.

N/A

Oxidizing Properties

N/A

Solvent Content

N/A

Explosive Properties

N/A

Water Content

N/A

Explosion Limits

N/A

Surface Tension

N/A

Vapor Pressure

N/A

Conductivity

N/A

SG/Density

N/A

Miscellaneous Data

N/A

Partition Coefficient

N/A

Solubility

N/A

STABILITY
Stable: Stable
Materials to Avoid: Strong oxidizing agents.

HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide, Nitrogen oxides.

HAZARDOUS POLYMERIZATION
Hazardous Polymerization: will not occur

RTECS NUMBER: QT0350000

LD50	LD50	LD50
Oral	Intraperitoneal	Intravenous
Rat	Rat	Rat
65 mg/kg	83 mg/kg	600 mg/kg

Ramarks :Behavioral Convulsions or effect on seizure threshold.

LD50
Parenteral
Rat
33500 UG/KG

LD5O
Oral
Mouse
65 mg/kg

LD50
Intraperitineal
Mouse
9100 UG/KG

LD50
Subcutaneous
Mouse
53 mg/kg

LD50
Intravenous
Mouse
300 UG/KG
Remarks: Behavioral: Rigidity (includes catalepsy)
Behavioral: Convulsions or effect on seizure threshold.

LD50
Intraperitoneal
Hamster
125 mg/kg

LD50
Parenteral
Frog
337 mg/kg

SIGNS AND SYMPTOMS OF EXPOSURE
Absorption into the body leads to the formation of methemoglobin which in sufficient concentration causes cyanosis. Onset may be delayed 2 to 4 hours or longer.

ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be fetal if absorbed through skin.
Eye Contact: May cause eye irritation.
Inhalation: May be fetal if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Ingestion: May be fetal if swallowed.

TARGET ORGAN INFORMATION
Central nervous system.

CHRONIC EXPOSURE - TERATOGEN

Result: Possible risk of congenital malformation in the fetus.
Species: Rat
Dose: 85503 UG/KG
Route of Applicaion : Implant
Exposure Time: ( 4-18D PREG )
Result: Specific Developmental
Abnormalities: Central nervous system.

Species: Rat
Dose: 126 MG/KG
Route of Application: Implant
Exposure Time: ( 1-21D PREG )
Result: Specific Developmental
Abnormalities: Central nervous system.

Species: Rat
Dose: 34 MG/KG
Route of Application: Implant
ExposureTime: ( 4-20D PREG )
Result: Specific Developmental
Abnormalities: Central nervous system.

Species: Mouse
Dose: 15391 UG/KG
Route of Application: Subcutaneous
Exposure Time: ( 1-6D PREG )
Result: Specific Developmental Abnormalities : Eye,ear.

CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Result :May cause reproductive disorders.

Species: Rat
Dose: 9500 UG/KG
Route of Application: Intraperitoneal
Exposure Time: ( 3-21D PREG )
Result: Effects on Newborn: Behavioral

Species: Rat
Dose: 285 UG/KG
Route of Application: Subcutaneous
Exposure Time: (1D MALE)
Result : Effects on fertility Mating performance (e. g., # sperm Positive females per # females mated; copulations per # estrus cycles).

Species: Rat
Dose: 75 mg/kg
Route of Application: Subcutaneous
Exposure Time: (1-5D)PREG )
Result: Effects on Fertility: Other measures of fertility

Species: Rat
Dose: 90 mg/kg
Route of Application: Subcutaneous
Exposure Time: (1-21D PREG )
Result: Effects on Fertility: Litter size ( e.g;# fetuses per litter; measured before birth) .
Effets on newborn: Sex ratio.
Effects on Newborn :Growth Statistics (e.gireduced weight gain).

Species: Rat
Dose: 102 mg/kg
Route of Application: Subcutaneous
Exposure Time: (4-20D PREG )
Result: Effects on Newborn: Growth Statistics (e.g. reduced weight gain) .Effects on Newborn: Biochemical and metabolic.

Species: Rat
Dose: 712 UG/KG
Route of Application: Implant
Exposure Time: (12D PREG )
Result: Effects on newborn: Biochemical and metabolic.

Species: Rat
Dose: 42 mg/kg
Route of Application: Implant
Exposure Time: (12-18D PREG )
Result: Effects on Newborn Biochemical and metabolic.
Effects on Newborn: Growth Statistics (e.gireduced weight gain) .

Species: Rat
Dose :102 mg/kg
Route of Application: Implant
Exposure Time: (4-20D PREG )
Result: Maternal Effects :Other effects: Effects on Newborn: Biochemical and metabolic.

Species: Monkey
Dose :50 UG/KG
Route of Application: Intravenous
Exposure Time: (1D PRE)
Result: Maternal Effects: Ovaries,fallopian tubes.

Species: Guinea pig
Dose :68 MG/KG
Route of Application: Subcutaneous
Exposure Time: (1-68D PREG )
Result: Effects on Newborn: Behavioral.

No data available

SUBSTANCE DISPOSAL

Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local environmental regulations.

RID/ADR
UN#: 1659
Class: 6.1
PG: II
Proper Shipping Name: Nicotine tartrate

IMDG
UN#: 1659
Class: 6.1
PG: II
ProperShipping Name: Nicotine tartrate
Marine Pollutant: No
Severe Marine Pollutant: No

lATA
UN#: 1659
Class: 6.1
PG: II
Proper Shipping Name: Nicotine tartrate
Inhalation Packing Group I: No

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER : 614-001-00-X
INDICATION OF DANGER: T+ -N
Very toxic.Dangerous for the environment.
R-PHRASES: 26/27/28-51/53
Toxic if swallowed. Very toxic in contact with skin. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
S-PHRASES: 13-28-45-61
Keep away from food, drink and animal feeding stuffs. After contact with skin, wash immediately with plenty of soapsuds. In case of accident or if you feel unwell, seek medical advice immediately (show the lable where possible). Avoid release to the environment. Refer to special instructions/safety data sheets.
Caution: Substance not yet fully tested (EU).
COUNTRY SPECIFIC INFORMATION
Germany
WGK : 2
Self- Classification

WARRANTY

The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. BGP International shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.

DISCLAIMER

For Industrial use only. Not for drug, household or other uses.

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